ea0063oc8.3 | Reproduction 1 | ECE2019
Rodriguez David Lopez
, Francisco Aylwin Carlos
, Gerard Arlette
, Blacher Silvia
, Tirelli Ezio
, Bourguignon Jean-Pierre
, Lomniczi Alejandro
, Parent Anne-Simone
Endocrine disruptors are a rising concern for public health due to their ubiquitous presence affecting reproductive development throughout generations. We aim at studying the transgenerational effect of an EDC mixture on female sexual development and reproduction. Female rats (F0 generation) were orally exposed to a mixture of 14 anti-androgenic and estrogenic EDCs or corn oil for 2 weeks before and throughout gestation and until weaning. The mixture was composed of plasticize...